非天然的含疊氮基單糖的砌塊。疊氮化物部分可用于通過化學選擇性連接化學方法進行修飾，包括 CuAAC、無銅點擊反應或 Staudinger 連接。乙?；黾恿嗽谠S多溶劑中的溶解度，使這種試劑的處理更容易。Ac4ManNAz 是含疊氮基的代謝糖蛋白標記試劑，能夠選擇性修飾蛋白質，可用于細胞標記、跟蹤和蛋白質組學分析。Ac4ManNAz是一種含疊氮基的代謝糖蛋白標記試劑，可以選擇性修飾蛋白質。Ac4ManNAz 可用于細胞標記、跟蹤和蛋白質組學分析。Ac4ManNAz 含有 Azide 基團，可以和含有 Alkyne 基團的分子發(fā)生銅催化的疊氮-炔環(huán)加成反應(CuAAc)。Ac4ManNAz 還可以和含有 DBCO 或 BCN 基團的分子發(fā)生菌株促進的炔-疊氮環(huán)加成反應 (SPAAC)。

靶點科技現(xiàn)貨N-azidoacetylmannosamine-tetraacylated (Ac4ManNAz) (CCT-1084)

精選參考文獻Selected References

1.Ranzinger, R., et al. (2020). Mass Spectrometric Method for the Unambiguous Profiling of Cellular Dynamic Glycosylation. ACS Chem. Biol., 15, 10, 2692-2701.

2.Loebel, C., et al. (2020). Metabolic Labeling to Probe the Spatiotemporal Accumulation of Matrix at the Chondrocyte–Hydrogel Interface. Adv. Funct. Mater.

3.Song, S., et al. (2020). In Situ One-Step Fluorescence Labeling Strategy of Exosomes via Bioorthogonal Click Chemistry for Real-Time Exosome Tracking In Vitro and In Vivo. Bioconjugate Chem., 31(5), 1562-74.

4.Kim, S. H., et al. (2014). Cell labeling and tracking method without distorted signals by phagocytosis of macrophages . Theranostics, 4 (4), 420-31.